Publications

Phosphatidylserine-Dependent Clearance of Damaged Red Blood Cells by Liver Sinusoidal Endothelial Cells in Alcohol-Related Liver Disease

Published Date

2026-04-29

Li S, Zheng C, Zha X, et al

• Siyuan Li
• Chaowen Zheng
• Xiaowei Zha
• Johannes Mueller
• Anne Dropmann
• Seddik Hammad
• Steven Dooley
• Sebastian Mueller

Journal

Biology

HISTAI: a valuable dataset with a valuable lesson

Published Date

2026-04-15

Hewitt KJ, Reitsam NG, Foersch S, Erber R, Zeng Q, Kather JN

• Katherine J Hewitt
• Nic G Reitsam
• Sebastian Foersch
• Ramona Erber
• Qinghe Zeng
• Jakob Nikolas Kather

Journal

The Journal of Pathology: Clinical Research

Establishing a long-term versatile culture system for functional mouse mammary organoids from single cells

Published Date

2026-03-19

Yuan L, Tang R, Xie S, Lin Z, Cai P, Cai S

• Lei Yuan
• Ruolan Tang
• Shaofang Xie
• Zuobao Lin
• Pei Cai
• Shang Cai

Journal

Nature Protocols

Semi-automated isolation of parenchymal and non-parenchymal liver cells from mice and humans with enhanced stellate cell fraction

Published Date

2026-03-14

Dropmann A, Dewidar B, Gould K, et al

• Anne Dropmann
• Bedair Dewidar
• Kerry Gould
• Raquel L. Baccetto
• Christoph Meyer
• Tiziana Caccamo
• Pia Erdoesi
• Şamil Ayvaz
• Andrea Scheffschick
• Georg Damm
• Daniel Seehofer
• Laura Kim Feiner
• Bianca Kruse
• Claudia Rubie
• Matthias Glanemann
• Vanessa Orth
• Emrullah Birgin
• Nuh Rahbari
• Matthias P. Ebert
• Steven Dooley
• Seddik Hammad

Journal

Cell & Bioscience

Hepatic management of toxic sterols after acute deletion of Cyp51 from cholesterol synthesis

Published Date

2026-03-01

Kreft T, Cokan KB, Skubic C, et al

• Tinkara Kreft
• Kaja Blagotinšek Cokan
• Cene Skubic
• Tadeja Režen
• Martina Perše
• Karmen Wechtersbach
• Nika Kojc
• Jera Jeruc
• Željko Debeljak
• Marija Heffer
• Madlen Matz-Soja
• Damjana Rozman

Journal

Journal of Biological Chemistry

Same Session Validation of a Custom‐Built 22G With the Commercial 25G System for EUS‐Guided Portal Pressure Gradient Measurement

Published Date

2026-02-26

Praktiknjo M, Farouk N, Wang Z, et al

• Michael Praktiknjo
• Nancy Farouk
• Zeyu Wang
• Juliana Stadtmann
• Dominik van de Loo
• Markus Kimmann
• Carina Gunia
• Jörn Arne Meier
• Frank Erhard Uschner
• Kai‐Henrik Peiffer
• Wim Laleman
• Jonel Trebicka
• Barbara Braden

Journal

United European Gastroenterology Journal

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

Published Date

2026-02-23

Kump A, Perne L, Koren Š, et al

• Ana Kump
• Leja Perne
• Špela Koren
• Eva Jarc Jovičić
• Nastja Feguš
• Carina Pinto Kozmus
• Michele Wölk
• Kristyna Brejchova
• Maria Fedorova
• Ondrej Kuda
• Toni Petan

Journal

The FEBS Journal

Hallucination filtering in radiology vision-language models using discrete semantic entropy

Published Date

2026-02-20

Wienholt P, Caselitz S, Siepmann R, et al

• Patrick Wienholt
• Sophie Caselitz
• Robert Siepmann
• Philipp Bruners
• Keno Bressem
• Christiane Kuhl
• Jakob Nikolas Kather
• Sven Nebelung
• Daniel Truhn

Journal

European Radiology

Benchmarking large language model-based agent systems for clinical decision tasks

Published Date

2026-02-18

Liu Y, Carrero ZI, Jiang X, et al

• Yunsong Liu
• Zunamys I. Carrero
• Xiaofeng Jiang
• Dyke Ferber
• Georg Wölflein
• Li Zhang
• Sanddhya Jayabalan
• Tim Lenz
• Zhouguang Hui
• Jakob Nikolas Kather

Journal

npj Digital Medicine

Prediction of Mutations and Outcome in Gastrointestinal Stromal Tumors with Deep Learning: A Multicenter, Multinational Study

Published Date

2026-02-03

Bonetti A, Le V, Carrero ZI, et al

• A. Bonetti
• V.L. Le
• Z. I. Carrero
• F. Wolf
• M. Gustav
• S.W. Lam
• L. Vanhersecke
• P. Sobczuk
• F. Le Loarer
• M. Lenarcik
• P. Rutkowski
• J. M. van Sabben
• N. Steeghs
• H. van Boven
• I. Machado
• S. Bagué
• S. Navarro
• E. Medina-Ceballos
• C. Agra
• F. Giner
• G. Tapia
• A. Hernández-Gallego
• G. Civantos Jubera
• M. Cuatrecasas
• S. Lopez-Prades
• R.E. Perret
• I. Soubeyran
• E. Khalifa
• L. Blouin
• E. Wardelmann
• A. Meurgey
• P. Collini
• A. Voloshin
• Y. Yatabe
• H. Hirano
• A. Gronchi
• T. Nishida
• O. Bouché
• J.F. Emile
• C. Ngo
• P. Hohenberger
• C. Cotarelo
• J. Jakob
• J.V.M.G. Bovee
• H. Gelderblom
• A. Szumera-Cieckiewicz
• M. Jean-Denis
• J. Bollard
• N. Lassau
• A. Lecesne
• J.Y. Blay
• A. Italiano
• A. Crombé
• J.M. Coindre
• J. N. Kather

Journal

preprint

The Taurine-Slc6a6 Axis Promotes Breast Cancer Progression by Alleviating Oxidative Stress and Accelerating Cell Cycle Progression

Published Date

2026-01-22

Cai P, Liu X, Lin M, et al

• Pei Cai
• Xiaoqin Liu
• Meizhen Lin
• Shaofang Xie
• Lei Yuan
• Zuobao Lin
• Yue Zhang
• Shang Cai

Journal

Cells

Modeling the dynamics of hepatic metabolism: the predominance of 12-hour rhythmicity in metabolic adaptation

Published Date

2026-01-09

Matz-Soja M, Körner C, Ott F, et al

• Madlen Matz-Soja
• Christiane Körner
• Fritzi Ott
• Janett Fischer
• Eugenia Marbach-Breitrück
• Christian Bergmann
• Ute Hofmann
• Andrej Shevchenko
• Iwona Wallach
• Kathrin Textoris-Taube
• Michael Mülleder
• Rolf Gebhardt
• Thomas Berg
• Nikolaus Berndt

Journal

Cellular and Molecular Life Sciences

Metabolic Signatures of Acinetobacter baumannii and Klebsiella pneumoniae Infections in Acute-on-chronic Liver Failure

Published Date

2026-01-01

Cadoli C, Arif S, Ballhorn W, et al

• Camilla Cadoli
• Sania Arif
• Wibke Ballhorn
• Angela Brieger
• Maximilian Joseph Brol
• Florence Castelli
• Hans-Peter Erasmus
• Julia Fischer
• Robert Gurke
• Lisa Hahnefeld
• Christophe Junot
• Nico Kraus
• Cristina Ortiz
• Robert Schierwagen
• Sara Garcia Torres
• Frank Erhard Uschner
• Volker Müller
• Jonel Trebicka
• Christoph Welsch
• Volkhard A.J. Kempf

Journal

Cellular and Molecular Gastroenterology and Hepatology

Identification of Circulating MiR-4651 as Novel Biomarker for Metabolic Dysfunction–associated Steatotic Liver Disease

Published Date

2026-01-01

Kirchmeyer M, Gaigneaux A, Servais FA, et al

• Mélanie Kirchmeyer
• Anthoula Gaigneaux
• Florence A. Servais
• Anita Arslanow
• Claudia Rubie
• Markus Casper
• Matthias Glanemann
• María L. Martínez-Chantar
• Marcin Krawczyk
• Frank Lammert
• Iris Behrmann

Journal

Gastro Hep Advances

Laser Capture Microdissection for Quantitative Shotgun Lipidomics

Published Date

2026-01-01

Journal

Methods in Molecular Biology

Human liver cholangiocyte organoids capture the heterogeneity of in vivo liver ductal epithelium

Published Date

2026-01-01

Bregante J, Don FK, Rost F, et al

• Javier Bregante
• Flaminia Kaluthantrige Don
• Fabian Rost
• André Gohr
• Germán Belenguer
• Franziska Baenke
• Dylan Liabeuf
• Jessie Pöche
• Clemens Schafmayer
• Michaela Wilsch-Bräuninger
• Sebastian Hinz
• Kevin O’ Holleran
• Daniel E. Stange
• Meritxell Huch

Journal

Cell Reports

Lactococcus A phages predict ACLF while Enterococcus B phages predict bacterial infection in decompensated cirrhosis

Published Date

2026-01-01

Espen LV, Brol MJ, Close L, et al

• Lore Van Espen
• Maximilian Joseph Brol
• Lila Close
• Robert Schierwagen
• Wenyi Gu
• Marisa I. Keller
• Boglarka Balogh
• Anthony Fullam
• Lander De Coninck
• Tomohiro Nakamura
• Michael Kuhn
• Peer Bork
• Wim Laleman
• Jasmohan S. Bajaj
• Maria Papp
• Bernd Schnabl
• Jonel Trebicka
• Jelle Matthijnssens

Journal

JHEP Reports

MASLD in the oldest-old: lack of association with cognition or functional autonomy and poor predictive utility of the hepatic steatosis index

Published Date

2025-12-24

Brol MJ, Groth M, Uschner FE, et al

• Maximilian Joseph Brol
• Martin Groth
• Frank Erhard Uschner
• Juliana Stadtmann
• Tina Schomacher
• Jonel Trebicka
• Michael Praktiknjo
• Elena Vorona

Journal

GeroScience

Human assembloids recapitulate periportal liver tissue in vitro

Published Date

2025-12-17

Yuan L, Dawka S, Kim Y, et al

• Lei Yuan
• Sagarika Dawka
• Yohan Kim
• Anke Liebert
• Fabian Rost
• Robert Arnes-Benito
• Franziska Baenke
• Christina Götz
• David Long Hin Tsang
• Andrea Schuhmann
• Anna Shevchenko
• Roberta Rezende de Castro
• Seunghee Kim
• Aleksandra Sljukic
• Anna M. Dowbaj
• Andrej Shevchenko
• Daniel Seehofer
• Dongho Choi
• Georg Damm
• Daniel E. Stange
• Meritxell Huch

Journal

Nature

Immunoglobulin G binding as a quantitative marker of hepatocellular death across acute and chronic liver injury

Published Date

2025-12-01

Neckermann L, Erdösi P, Dropmann A, et al

• Lukas Neckermann
• Pia Erdösi
• Anne Dropmann
• Amnah Othman
• Johanna Weinert
• Jan Albin
• Stephanie D. Wolf
• Brigitte begher-Tibbe
• Iris von Recklinghausen
• Tiziana Caccamo
• Matthias P. Ebert
• Johannes G. Bode
• Jan Hengstler
• Steven Dooley
• Seddik Hammad

Journal

preprint

On the different flavours of practical identifiability

Published Date

2025-12-01

Heinrich M, Arutjunjan R, Timmer J

• Mio Heinrich
• Rafael Arutjunjan
• Jens Timmer

Journal

Current Opinion in Systems Biology

NADPH oxidase 1/4 dual inhibition impairs transforming growth factor-beta protumorigenic effects in cholangiocarcinoma cancer-associated fibroblasts

Published Date

2025-12-01

Amengual J, Gonzalez-Sanchez E, Yáñez-Bartolome M, et al

• Josep Amengual
• Ester Gonzalez-Sanchez
• Mariana Yáñez-Bartolome
• Laura Sererols-Viñas
• Aashreya Ravichandra
• Celia Guiton
• Noel P. Fuste
• Ania Alay
• Sara Hijazo-Pechero
• Beatriz Martín-Mur
• Marta Gut
• Anna Esteve-Codina
• Ana Cantos-Cortes
• Rut Espinosa-Sotelo
• Emilio Ramos
• Teresa Serrano
• Mariona Calvo
• Berta Laquente
• Joana Ferrer
• Gabriel Pons
• Andrés Mendez-Lucas
• Steven Dooley
• Sumera I. Ilyas
• Marie Vallette
• Lynda Aoudjehane
• Marie Lequoy
• Laura Fouassier
• Cédric Coulouarn
• Silvia Affò
• Alexander Scheiter
• Diego F. Calvisi
• Tian V. Tian
• Isabel Fabregat
• Javier Vaquero

Journal

Signal Transduction and Targeted Therapy

Stage-dependent effects of systemic ASBT inhibition in a cholestasis-induced cholemic nephropathy mouse model

Published Date

2025-12-01

Ghallab A, Myllys M, González D, et al

• Ahmed Ghallab
• Maiju Myllys
• Daniela González
• Adrian Friebel
• Zaynab Hobloss
• Reham Hassan
• Hannah Schmidt
• Qasim Siddiqui
• Deng Zhipeng
• Rama Hendawi
• Brigitte Begher-Tibbe
• Joerg Reinders
• Katharina Derksen
• Ute Hofmann
• Julia C. Duda
• Lucia Ameis
• Kathrin Möllenhoff
• Abdellatief Seddek
• Noha Abdelmageed
• Ellen Strängberg
• Peter Åkerblad
• Mihael Vucur
• Tom Luedde
• Guido Stirnimann
• Matthias Schwab
• Tahany Abbas
• Benedikt Hild
• Hartmut Schmidt
• Saul J. Karpen
• Benedikt Simbrunner
• Mattias Mandorfer
• Jörg Rahnenführer
• Karolina Edlund
• Stefan Hoehme
• Michael Trauner
• Paul A. Dawson
• Erik Lindström
• Jan G. Hengstler

Journal

JHEP Reports

OmniPath: integrated knowledgebase for multi-omics analysis

Published Date

2025-11-18

Türei D, Schaul J, Palacio-Escat N, et al

• Dénes Türei
• Jonathan Schaul
• Nicolàs Palacio-Escat
• Balázs Bohár
• Yunfan Bai
• Francesco Ceccarelli
• Elif Çevrim
• Macabe Daley
• Melih Darcan
• Daniel Dimitrov
• Tunca Doğan
• Daniel Domingo-Fernández
• Aurelien Dugourd
• Attila Gábor
• Lejla Gul
• Benjamin A Hall
• Charles Tapley Hoyt
• Olga Ivanova
• Michal Klein
• Toby Lawrence
• Diego Mañanes
• Dezső Módos
• Sophia Müller-Dott
• Márton Ölbei
• Christina Schmidt
• Bünyamin Şen
• Fabian J Theis
• Atabey Ünlü
• Erva Ulusoy
• Alberto Valdeolivas
• Tamás Korcsmáros
• Julio Saez-Rodriguez

Journal

Nucleic Acids Research

Human Hepatocytes in Experimental Steatosis: Influence of Donor Sex and Sex Hormones

Published Date

2025-11-12

Seidemann L, Rohm CM, Stilkerich A, et al

• Lena Seidemann
• Carolin Marie Rohm
• Anna Stilkerich
• René Hänsel
• Christina Götz
• Daniel Seehofer
• Georg Damm

Journal

Biomedicines

Diclofenac and acetaminophen dim the acute-phase response but amplify expression of the iron regulator hepcidin in liver cancer cells

Published Date

2025-11-01

Zeilfelder A, Vanlier J, Mölders C, et al

• Anja Zeilfelder
• Joep Vanlier
• Christina Mölders
• Philipp Kastl
• Barbara Helm
• Sebastian Burbano de Lara
• Till Möcklinghoff
• Nantia Leonidou
• Elisa Holstein
• Artyom Vlasov
• Alexander Held
• Silvana Wilken
• Katrin Hoffmann
• Gerda Schicht
• Andrea Scheffschick
• Markella Katerinopoulou
• Esther Giehl-Brown
• Christoph Kahlert
• Christoph Michalski
• Daniel Seehofer
• Georg Damm
• Martina U. Muckenthaler
• Marcel Schilling
• Jens Timmer
• Ursula Klingmüller

Journal

Cell Systems

In Vitro Characterization of the Published Glypican-3-Targeting Peptide TJ12P2 Reveals a Lack of Specificity and Potency

Published Date

2025-11-01

Burger E, Hill C, Wodtke R, et al

• Eva-Maria Burger
• Charlice Hill
• Robert Wodtke
• Kristof Zarschler
• Markus Laube
• Cornelius K. Donat
• Sandra Hauser
• Klaus Kopka
• Jens Pietzsch
• Sven Stadlbauer

Journal

Pharmaceuticals

Insights into the GALAD score: A new optimal cut-off for hepatocellular carcinoma

Published Date

2025-10-28

Villa E, Donghia R, Coletta S, et al

• Erica Villa
• Rossella Donghia
• Sergio Coletta
• Caterina Bonfiglio
• Rosina Maria Critelli
• Anna Ancona
• Endrit Shahini
• Palma Aurelia Iacovazzi
• Raffaele Cozzolongo
• Francesca Pavone
• Nicola Carella
• Patrizia Pontisso
• Andrea Martini
• Sherin Al Aoua
• Heike Bantel
• Gianluigi Giannelli

Journal

World Journal of Gastroenterology

Novel Ruthenacarborane–NSAID Conjugates

Published Date

2025-10-22

Sonam S, Mojić M, Gordić V, et al

• Sonam Sonam
• Marija Mojić
• Vuk Gordić
• Markus Laube
• Jonas Schädlich
• Jens Pietzsch
• Adrian Nicoara
• Luiza Gaina
• Sanja Mijatović
• Danijela Maksimović-Ivanić
• Goran N. Kaluđerović
• Evamarie Hey-Hawkins

Journal

Molecules

Towards sustainable lipidomics: computational screening and experimental validation of chloroform-free alternatives for lipid extraction

Published Date

2025-10-04

Venturi A, Wölk M, Penkov S, Cruciani G, Fedorova M, Goracci L

• Andrea Venturi
• Michele Wölk
• Sider Penkov
• Gabriele Cruciani
• Maria Fedorova
• Laura Goracci

Journal

Analytical and Bioanalytical Chemistry

Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set

Published Date

2025-10-02

Distler U, Yoo HB, Kardell O, et al

• Ute Distler
• Han Byul Yoo
• Oliver Kardell
• Dana Hein
• Malte Sielaff
• Marian Scherer
• Anna M. Jozefowicz
• Christian Leps
• David Gomez-Zepeda
• Christine von Toerne
• Juliane Merl-Pham
• Teresa K. Barth
• Johanna Tüshaus
• Pieter Giesbertz
• Torsten Müller
• Georg Kliewer
• Karim Aljakouch
• Barbara Helm
• Henry Unger
• Dario L. Frey
• Dominic Helm
• Luisa Schwarzmüller
• Oliver Popp
• Di Qin
• Susanne I. Wudy
• Ludwig Roman Sinn
• Julia Mergner
• Christina Ludwig
• Axel Imhof
• Bernhard Kuster
• Stefan F. Lichtenthaler
• Jeroen Krijgsveld
• Ursula Klingmüller
• Philipp Mertins
• Fabian Coscia
• Markus Ralser
• Michael Mülleder
• Stefanie M. Hauck
• Stefan Tenzer

Journal

Nature Communications

Transforming Growth Factor-β Signaling in Alcohol-Associated Liver Disease

Published Date

2025-10-01

Zou H, Wang S, Huang C, Dooley S, Meindl-Beinker NM

• Huihui Zou
• Sai Wang
• Chenjun Huang
• Steven Dooley
• Nadja M. Meindl-Beinker

Journal

The American Journal of Pathology

AB024. MIST: a weakly supervised deep learning system for multicenter diagnosis of mediastinal tumors

Published Date

2025-09-01

Jiang X, Liang H, He J, Han Y, Kather JN, Leng X

• Xiaofeng Jiang
• Hengrui Liang
• Jianxing He
• Yongtao Han
• Jakob Nikolas Kather
• Xuefeng Leng

Journal

Mediastinum

Evaluating a population-based screening programme for early detection of liver fibrosis and cirrhosis in primary care in Germany: a cost assessment study

Published Date

2025-09-01

Ortner J, Ewijk RV, Velthuis L, et al

• Julia Ortner
• Reyn Van Ewijk
• Louis Velthuis
• Christian Labenz
• Anita Arslanow
• Marc Nguyen-Tat
• Marcus-Alexander Wörns
• Matthias Christian Reichert
• Erik Farin-Glattacker
• Harald Binder
• Urs A Fichtner
• Erika Graf
• Dominikus Stelzer
• Peter R Galle
• Frank Lammert

Journal

BMJ Open

SputOMICs identifies common and distinct markers in cystic fibrosis and chronic obstructive pulmonary disease

Published Date

2025-08-20

Boutin S, Frey D, Helm B, et al

• Sebastien Boutin
• Dario Frey
• Barbara Helm
• Matteo Guerra
• Matthias Hagner
• Junyan Lu
• Susanne Dittrich
• Sabine Wege
• Ralf Eberhardt
• Felix Herth
• Olaf Sommerburg
• Carsten Schultz
• Alexander Dalpke
• Ursula Klingmueller
• Marcus Mall

Journal

preprint

The interplay between biomechanics and cell kinetics explains the spatial pattern in liver fibrosis

Published Date

2025-08-02

Zhao J, Hammad S, Langlard Md, et al

• Jieling Zhao
• Seddik Hammad
• Mathieu de Langlard
• Pia Erdoesi
• Yueni Li
• Paul Van Liedekerke
• Andreas Buttenschoen
• Manuel Winkler
• Sina W. Kürschner
• Philipp-Sebastian Reiners-Koch
• Niels Grabe
• Björn Hartleben
• Stephanie D. Wolf
• Johannes Bode
• Jan G. Hengstler
• Matthias P. Ebert
• Steven Dooley
• Dirk Drasdo

Journal

preprint

Investigation and Distinction of Energy Metabolism in Proliferating Hepatocytes and Hepatocellular Carcinoma Cells

Published Date

2025-08-01

Nerusch J, Schicht G, Herzog N, Küpper J, Seehofer D, Damm G

• Julia Nerusch
• Gerda Schicht
• Natalie Herzog
• Jan-Heiner Küpper
• Daniel Seehofer
• Georg Damm

Journal

Cells

Deep neural cellular Potts models

Published Date

2025-08-01

Minartz K, D’Hondt T, Hillmann L, Starruß J, Brusch L, Menkovski V

• Koen Minartz
• Tim D’Hondt
• Leon Hillmann
• Jörn Starruß
• Lutz Brusch
• Vlado Menkovski

Journal

Freiburg index of post-TIPS survival (FIPS) identifies patients at risk of further decompensation and ACLF after TIPS

Published Date

2025-08-01

Sturm L, Schultheiss M, Stöhr F, et al

• Lukas Sturm
• Michael Schultheiss
• Fabian Stöhr
• Christian Labenz
• Benjamin Maasoumy
• Anja Tiede
• Michael Praktiknjo
• Leon Louis Seifert
• Timo Alexander Auer
• Uli Fehrenbach
• Felix Piecha
• Aenne Harberts
• Johannes Kluwe
• Tony Bruns
• Maike Rebecca Pollmanns
• Johannes Chang
• Jakub Grobelski
• Christian Jansen
• Carsten Meyer
• Marlene Reincke
• Charlotte Rohrer
• Sina Rastin Philipp Arbabi
• Markus Kimmann
• Cristina Ripoll
• Alexander Zipprich
• Jan Hinrichs
• Michael Koehler
• Jonel Trebicka
• Roman Kloeckner
• Cornelius Engelmann
• Robert Thimme
• Dominik Bettinger

Journal

Journal of Hepatology

Mouse precision-cut liver and kidney slices: an optimized <i>ex vivo</i> model for acute toxicity testing

Published Date

2025-07-25

Spruck C, Bousejra G, Erbay A, et al

• Christiane Spruck
• Ghizlan Bousejra
• Ahmed Erbay
• Sonja Herbrich
• Andreas Dimitriadis
• Zoe Röntgen
• Frauke Roolfs
• Isaac Musong Mboni-Johnston
• Gerhard Fritz
• Seddik Hammad
• Nicole Schupp

Journal

preprint

Overcoming regulatory barriers to the implementation of AI agents in healthcare.

Published Date

2025-07-18

Freyer O, Jayabalan S, Kather JN, Gilbert S

• O. Freyer
• S. Jayabalan
• J. N. Kather
• S. Gilbert

Journal

Nat Med

The barriers for uptake of artificial intelligence in hepatology and how to overcome them

Published Date

2025-07-17

Clusmann J, Balaguer-Montero M, Bassegoda O, et al

• Jan Clusmann
• Maria Balaguer-Montero
• Octavi Bassegoda
• Carolin V. Schneider
• Tobias Seraphin
• Ellis Paintsil
• Tom Luedde
• Raquel Perez Lopez
• Julien Calderaro
• Stephen Gilbert
• Thomas Marjot
• Ashley Spann
• Debbie L. Shawcross
• Sabela Lens
• Eric Trépo
• Jakob Nikolas Kather

Journal

Journal of Hepatology

ECM1 expression in chronic liver disease: Regulation by EGF/STAT1 and IFNgamma/NRF2 signalling.

Published Date

2025-07-17

Li Y, Huang C, Fan W, et al

• Y. Li
• C. Huang
• W. Fan
• S. Hammad
• C. Geraud
• L. Berger
• S. Wang
• Y. Yao
• C. Tong
• C. Rubie
• L. K. Feiner
• Z. C. Nwosu
• F. Link
• P. Erdosi
• W. Pioronska
• K. Gould
• C. Meyer
• R. Feng
• H. Liu
• C. Shao
• B. Sun
• H. Ding
• R. Liebe
• M. P. A. Ebert
• H. Weng
• M. Glanemann
• C. Gao
• P. T. Dijke
• S. Dooley
• S. Wang

Journal

JHEP Rep

LC-MS and High-Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry.

Published Date

2025-07-01

Nepachalovich P, Bonciarelli S, Bendoula GL, et al

• P. Nepachalovich
• S. Bonciarelli
• G. Lombardi Bendoula
• J. Desantis
• M. Eleuteri
• C. Thiele
• L. Goracci
• M. Fedorova

Journal

Angew Chem Int Ed Engl

Exploring the Role of Peripheral Macrophages in Glioma Progression: The Metabolic Significance of Cyclooxygenase-2 (COX-2)

Published Date

2025-06-27

Pietzsch J, Toussaint M, Donat CK, et al

• Jens Pietzsch
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2025-06-07

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2025-06-05

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2024-11-19

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Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity

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2024-11-08

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2024-10-16

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Pregnancy alters fatty acid metabolism, glucose regulation, and detoxification of the liver in synchrony with biomechanical property changes

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2024-10-01

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2024-09-29

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FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

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2024-09-26

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Exploring the metabolic profile of A. baumannii for antimicrobial development using genome-scale modeling

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2024-09-23

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PLOS Pathogens

Between Theory and Practice: Computational/Experimental Integrated Approaches to Understand the Solubility and Lipophilicity of PROTACs

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2024-09-13

Venturi A, Bona SD, Desantis J, et al

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Identification of PRMT5 as a therapeutic target in cholangiocarcinoma

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Direct Ingestion of Oxidized Red Blood Cells (Efferocytosis) by Hepatocytes.

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Hepat Med

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Nature Methods

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bioRxiv

Genome-scale model of <i>Rothia mucilaginosa</i> predicts gene essentialities and reveals metabolic capabilities

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Microbiology Spectrum

Thy‐1 restricts steatosis and liver fibrosis in steatotic liver disease

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2024-05-04

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Liver International

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Journal

Redox Biology

Terlipressin therapy is associated with increased risk of colonisation with multidrug‐resistant bacteria in patients with decompensated cirrhosis

Published Date

2024-02-27

Mücke MM, Hernández‐Tejero M, Gu W, et al

• Marcus M. Mücke
• María Hernández‐Tejero
• Wenyi Gu
• Michael Kuhn
• Malte Janz
• Marisa I. Keller
• Anthony Fullam
• Laura Altepeter
• Victoria T. Mücke
• Fabian Finkelmeier
• Katharina M. Schwarzkopf
• Carla Cremonese
• Peter‐Merton Hunyady
• Myriam W. Heilani
• Frank Erhard Uschner
• Robert Schierwagen
• Maximilian J. Brol
• Julia Fischer
• Sabine Klein
• Kai‐Henrik Peiffer
• Michael Hogardt
• Saeed Shoaie
• Minneke J. Coenraad
• Jörg Bojunga
• Vicente Arroyo
• Stefan Zeuzem
• Volkhard A. J. Kempf
• Christoph Welsch
• Wim Laleman
• Peer Bork
• Javier Fernandez
• Jonel Trebicka
• MICROB‐PREDICT and PREDICT Study Group of the EASL‐CLIF Consortium

Journal

Alimentary Pharmacology & Therapeutics

Association between endotoxemia and blood no in the portal circulation of cirrhotic patients: results of a pilot study

Published Date

2024-02-26

Bartimoccia S, Praktiknjo M, Nocella C, et al

• Simona Bartimoccia
• Michael Praktiknjo
• Cristina Nocella
• Robert Schierwagen
• Vittoria Cammisotto
• Christian Jansen
• Luca Cristiano
• Valentina Castellani
• Johannes Chang
• Roberto Carnevale
• Sofia Maiucci
• Frank Erhard Uschner
• Pasquale Pignatelli
• Maximilian Joseph Brol
• Jonel Trebicka
• Francesco Violi

Journal

Internal and Emergency Medicine

Lysis buffer selection guidance for mass spectrometry-based global proteomics including studies on the intersection of signal transduction and metabolism (preprint)

Published Date

2024-02-21

Helm B, Hansen P, Lai L, et al

• Barbara Helm
• Pauline Hansen
• Li Lai
• Luisa Schwarzmüller
• Simone M. Clas
• Annika Richter
• Max Ruwolt
• Fan Liu
• Dario Frey
• Lorenza A. D’Alessandro
• Wolf-Dieter Lehmann
• Marcel Schilling
• Dominic Helm
• Dorothea Fiedler
• Ursula Klingmüller

Journal

bioRxiv

A liver digital twin for in silico testing of cellular and inter-cellular mechanisms in regeneration after drug-induced damage.

Published Date

2024-02-16

Zhao J, Ghallab A, Hassan R, Dooley S, Hengstler JG, Drasdo D

• J. Zhao
• A. Ghallab
• R. Hassan
• S. Dooley
• J. G. Hengstler
• D. Drasdo

Journal

iScience

A dynamic culture system that models the intricacy of the mammary gland

Published Date

2024-02-05

Yuan L

• Lei Yuan

Journal

Nature Reviews Molecular Cell Biology

Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL - a randomised clinical biomarker validation trial

Published Date

2024-02-01

Torp N, Israelsen M, Coenraad M, et al

• Nikolaj Torp
• Mads Israelsen
• Minneke Coenraad
• Maria Papp
• Debbie Shawcross
• Marko Korenjak
• Paolo Angeli
• Wim Laleman
• Adria Juanola
• Pere Gines
• Jonel Trebicka
• Aleksander Krag

Journal

BMJ Open

Quantitative proteomics study of carnosine effect in an animal model of Western diet‐induced nonalcoholic fatty liver disease

Published Date

2024-01-27

Moreto F, Garcia JL, Ferreira ALdA, et al

• Fernando Moreto
• Jéssica Leite Garcia
• Ana Lúcia dos Anjos Ferreira
• Silvia Radrezza
• Mariane Róvero Costa
• Guilherme Ribeiro Romualdo
• Nubia Alves Grandini
• Giancarlo Aldini
• Camila Renata Correa
• Alfonsina D'Amato

Journal

Journal of Biochemical and Molecular Toxicology

Impact of Viscosity on Human Hepatoma Spheroids in Soft Core–Shell Microcapsules

Published Date

2024-01-25

Peng X, Janićijević Ž, Lemm S, et al

• Xuan Peng
• Željko Janićijević
• Sandy Lemm
• Sandra Hauser
• Michael Knobel
• Jens Pietzsch
• Michael Bachmann
• Larysa Baraban

Journal

Advanced Healthcare Materials

Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease

Published Date

2024-01-12

Burbano de Lara S, Kemmer S, Biermayer I, et al

• Sebastian Burbano de Lara
• Svenja Kemmer
• Ina Biermayer
• Svenja Feiler
• Artyom Vlasov
• Lorenza A D’Alessandro
• Barbara Helm
• Christina Mölders
• Yannik Dieter
• Ahmed Ghallab
• Jan G Hengstler
• Christiane Körner
• Madlen Matz-Soja
• Christina Götz
• Georg Damm
• Katrin Hoffmann
• Daniel Seehofer
• Thomas Berg
• Marcel Schilling
• Jens Timmer
• Ursula Klingmüller

Journal

Molecular Systems Biology

The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation

Published Date

2024-01-01

Wang S, Link F, Han M, et al

• Sai Wang
• Frederik Link
• Mei Han
• Roohi Chaudhary
• Anastasia Asimakopoulos
• Roman Liebe
• Ye Yao
• Seddik Hammad
• Anne Dropmann
• Marinela Krizanac
• Claudia Rubie
• Laura Kim Feiner
• Matthias Glanemann
• Matthias P.A. Ebert
• Ralf Weiskirchen
• Yoav I. Henis
• Marcelo Ehrlich
• Steven Dooley

Journal

Cellular and Molecular Gastroenterology and Hepatology

Insulin Determines Transforming Growth Factor β Effects on Hepatocyte Nuclear Factor 4α Transcription in Hepatocytes

Published Date

2024-01-01

Feng R, Tong C, Lin T, et al

• Rilu Feng
• Chenhao Tong
• Tao Lin
• Hui Liu
• Chen Shao
• Yujia Li
• Carsten Sticht
• Kejia Kan
• Xiaofeng Li
• Rui Liu
• Sai Wang
• Shanshan Wang
• Stefan Munker
• Hanno Niess
• Christoph Meyer
• Roman Liebe
• Matthias P. Ebert
• Steven Dooley
• Hua Wang
• Huiguo Ding
• Hong-Lei Weng

Journal

The American Journal of Pathology

NME4 mediates metabolic reprogramming and promotes nonalcoholic fatty liver disease progression

Published Date

2023-12-14

Xie S, Yuan L, Sui Y, Feng S, Li H, Li X

• Shaofang Xie
• Lei Yuan
• Yue Sui
• Shan Feng
• Hengle Li
• Xu Li

Journal

EMBO Reports

Extracellular Matrix Protein 1 Attenuates Hepatic Fibrosis by Inhibiting TSP-, ADAMTS-, and MMP-Mediated Latent TGF-β1 Activation

Published Date

2023-12-12

Link F, Li Y, Zhao J, et al

• Frederik Link
• Yujia Li
• Jieling Zhao
• Stefan Munker
• Weiguo Fan
• Zeribe Nwosu
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• Seddik Hammad
• Roman Liebe
• Hui Liu
• Chen Shao
• Bing Sun
• Natalie J. Török
• Huiguo Ding
• Matthias P. A. Ebert
• Hong-Lei Weng
• Peter ten Dijke
• Dirk Drasdo
• Steven Dooley
• Sai Wang

Journal

preprint

Rapid dexamethasone treatment inhibits LPS-induced cytokine storm in mice

Published Date

2023-12-07

Zhang F, Xiao L, Li Y, et al

• Fen Zhang
• Lanlan Xiao
• Yujia Li
• Rilu Feng
• Menghao Zhou
• Shima Tang
• Roman Liebe
• Matthias P Ebert
• Steven Dooley
• Lanjuan Li
• Hong-Lei Weng

Journal

preprint

Hepatocellular loss of mTOR aggravates tumor burden in nonalcoholic steatohepatitis-related HCC

Published Date

2023-12-01

Kroh A, Walter J, Fragoulis A, et al

• Andreas Kroh
• Jeanette Walter
• Athanassios Fragoulis
• Diana Möckel
• Twan Lammers
• Fabian Kiessling
• Julia Andruszkow
• Christian Preisinger
• Maren Egbert
• Long Jiao
• Roman M. Eickhoff
• Daniel Heise
• Nikolaus Berndt
• Thorsten Cramer
• Ulf Peter Neumann
• Antje Egners
• Tom Florian Ulmer

Journal

Neoplasia

Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression

Published Date

2023-12-01

Hiebinger F, Kudulyte A, Chi H, et al

• Felix Hiebinger
• Aiste Kudulyte
• Huanting Chi
• Sebastian Burbano De Lara
• Doroteja Ilic
• Barbara Helm
• Hendrik Welsch
• Viet Loan Dao Thi
• Ursula Klingmüller
• Marco Binder

Journal

Cancer Cell International

Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities

Published Date

2023-11-10

Müller-Dott S, Tsirvouli E, Vazquez M, et al

• Sophia Müller-Dott
• Eirini Tsirvouli
• Miguel Vazquez
• Ricardo O Ramirez Flores
• Pau Badia-i-Mompel
• Robin Fallegger
• Dénes Türei
• Astrid Lægreid
• Julio Saez-Rodriguez

Journal

Nucleic Acids Research

Reconstruction of dynamic mammary mini gland in vitro for normal physiology and oncogenesis

Published Date

2023-11-02

Yuan L, Xie S, Bai H, et al

• Lei Yuan
• Shaofang Xie
• Huiru Bai
• Xiaoqin Liu
• Pei Cai
• Jing Lu
• Chunhui Wang
• Zuobao Lin
• Shuying Li
• Yajing Guo
• Shang Cai

Journal

Nature Methods

FitMultiCell: simulating and parameterizing computational models of multi-scale and multi-cellular processes.

Published Date

2023-11-01

Alamoudi E, Schalte Y, Muller R, et al

• E. Alamoudi
• Y. Schalte
• R. Muller
• J. Starruss
• N. Bundgaard
• F. Graw
• L. Brusch
• J. Hasenauer

Journal

Bioinformatics

Epidemiology of liver transplantation and post-LT complications in Germany: nationwide study (2005–2018)

Published Date

2023-09-18

Gu W, Schaaf L, Hortlik H, et al

• Wenyi Gu
• Louisa Schaaf
• Hannah Hortlik
• Yasmin Zeleke
• Maximilian J. Brol
• Andreas A. Schnitzbauer
• Wolf O. Bechstein
• Stefan Zeuzem
• Alexander Queck
• Kai-Henrik Peiffer
• Michael Tischendorf
• Andreas Pascher
• Wim Laleman
• Michael Praktiknjo
• Martin S. Schulz
• Frank E. Uschner
• Florian Rennebaum
• Jonel Trebicka

Journal

European Journal of Gastroenterology & Hepatology

Use and outcome of TIPS in hospitalized patients in Germany: A Nationwide study (2007–2018)

Published Date

2023-09-15

Gu W, Zeleke Y, Hortlik H, et al

• Wenyi Gu
• Yasmin Zeleke
• Hannah Hortlik
• Louisa Schaaf
• Frank E. Uschner
• Martin Schulz
• Michael Tischendorf
• Kai-Henrik Peiffer
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• Markus Kimmann
• Thomas Vogl
• Michael Köhler
• Carsten Meyer
• Alexander Gerbes
• Martin Rössle
• Wim Laleman
• Alexander Zipprich
• Christian Steib
• Michael Praktiknjo
• Jonel Trebicka
• German TIPS Working Group

Journal

Hepatology Communications

Lysyl Oxidases as Targets for Cancer Therapy and Diagnostic Imaging

Published Date

2023-09-15

Löser R, Kuchar M, Wodtke R, et al

• Reik Löser
• Manuela Kuchar
• Robert Wodtke
• Christin Neuber
• Birgit Belter
• Klaus Kopka
• Lakshmi Santhanam
• Jens Pietzsch

Journal

ChemMedChem

Hepatokine‐based identification of fibrotic NASH and improved risk stratification in a multicentre cohort of NAFLD patients

Published Date

2023-08-03

Franck M, John K, Al Aoua S, et al

• Martin Franck
• Katharina John
• Sherin Al Aoua
• Monika Rau
• Andreas Geier
• Jörn M. Schattenberg
• Heiner Wedemeyer
• Klaus Schulze‐Osthoff
• Heike Bantel

Journal

Liver International

An integrative experimental and computational twin modeling approach to understand clonal dynamics in the normal liver

Published Date

2023-08-01

Drasdo D, Zhao J

• Dirk Drasdo
• Jieling Zhao

Journal

Journal of Hepatology

Myostatin is associated with the presence and development of acute-on-chronic liver failure

Published Date

2023-08-01

Ruiz-Margáin A, Pohlmann A, Lanzerath S, et al

• Astrid Ruiz-Margáin
• Alessandra Pohlmann
• Silke Lanzerath
• Melanie Langheinrich
• Alejandro Campos-Murguía
• Berenice M. Román-Calleja
• Robert Schierwagen
• Sabine Klein
• Frank Erhard Uschner
• Maximilian Joseph Brol
• Aldo Torre-Delgadillo
• Nayelli C. Flores-García
• Michael Praktiknjo
• Ricardo U. Macías Rodríguez
• Jonel Trebicka

Journal

JHEP Reports

Anti-Cancer Prodrug Cyclophosphamide Exerts Thrombogenic Effects on Human Venous Endothelial Cells Independent of CYP450 Activation—Relevance to Thrombosis

Published Date

2023-08-01

Krüger-Genge A, Köhler S, Laube M, et al

• Anne Krüger-Genge
• Susanne Köhler
• Markus Laube
• Vanessa Haileka
• Sandy Lemm
• Karolina Majchrzak
• Sarah Kammerer
• Christian Schulz
• Joachim Storsberg
• Jens Pietzsch
• Jan-Heiner Küpper
• Friedrich Jung

Journal

Cells

An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH

Published Date

2023-08-01

Tacke F, Puengel T, Loomba R, Friedman SL

• Frank Tacke
• Tobias Puengel
• Rohit Loomba
• Scott L. Friedman

Journal

Journal of Hepatology

Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study

Published Date

2023-08-01

Serra-Burriel M, Juanola A, Serra-Burriel F, et al

• Miquel Serra-Burriel
• Adrià Juanola
• Feliu Serra-Burriel
• Maja Thiele
• Isabel Graupera
• Elisa Pose
• Guillem Pera
• Ivica Grgurevic
• Llorenç Caballeria
• Salvatore Piano
• Laurens van Kleef
• Mathias Reichert
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• Juan M Pericàs
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• Emmanuel A Tsochatztis
• Indra Neil Guha
• Montserrat Garcia-Retortillo
• Rosario Hernández
• Jordi Hoyo
• Matilde Fuentes
• Carmen Expósito
• Alba Martínez
• Patricia Such
• Anita Madir
• Sönke Detlefsen
• Marta Tonon
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• Ann T Ma
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• Céline Fournier
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• Paolo Angeli
• Robert J de Knegt
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• Peter Galle
• Vincent Wai-Sun Wong
• Núria Fabrellas
• Laurent Castera
• Aleksander Krag
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• Pere Ginès
• Marifé Alvarez
• Peter Andersen
• Paolo Angeli
• Alba Ardèvol
• Anita Arslanow
• Luca Beggiato
• Zahia Ben Abdesselam
• Lucy Bennett
• Bajiha Boutouria
• Alessandra Brocca
• M. Teresa Broquetas
• Llorenç Caballeria
• Valeria Calvino
• Judith Camacho
• Aura Capdevila
• Marta Carol
• Laurent Castera
• Marta Cervera
• Fernando Cucchietti
• Anna de Fuentes
• Rob de Knegt
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• Sonke Detlefsen
• Alba Diaz
• José Diéguez Bande
• Vanessa Esnault
• Núria Fabrellas
• Josep Lluis Falcó
• Rosa Fernández
• Céline Fournier
• Matilde Fuentes
• Peter Galle
• Edgar García
• Montserrat García-Retortillo
• Esther Garrido
• Pere Ginès
• Rosa Gordillo Medina
• Jordi Gratacós-Ginès
• Isabel Graupera
• Ivica Grgurevic
• Indra Neil Guha
• Eva Guix
• Johanne Kragh Hansen
• Rebecca Harris
• Elena Hernández Boluda
• Rosario Hernández-Ibañez
• Jordi Hoyo
• Arfan Ikram
• Simone Incicco
• Mads Israelsen
• Marta Juan
• Adrià Juanola
• Ralf Kaiser
• Patrick S Kamath
• Tom H Karlsen
• Maria Kjærgaard
• Marko Korenjak
• Aleksander Krag
• Marcin Krawczyk
• Philippe Laboulaye
• Irina Lambert
• Frank Lammert
• Simon Langkjær Sørensen
• Cristina Laserna-Jiménez
• Sonia Lazaro Pi
• Elsa Ledain
• Vincent Levy
• Katrine Prier Lindvig
• Anne Llorca
• Vanessa Londoño
• Guirec Loyer
• Ann T. Ma
• Anita Madir
• Michael Manns
• Denise Marshall
• M. Lluïsa Martí
• Sara Martínez
• Ricard Martínez Sala
• Roser Masa-Font
• Jane Møller Jensen
• Rosa M Morillas
• Laura Muñoz
• Ruth Nadal
• Laura Napoleone
• JM Navarrete
• Phillip N Newsome
• Vibeke Nielsen
• Martina Pérez
• Juan Manuel Pericás-Pulido
• Salvatore Piano
• Judit Pich
• Elisa Pose
• Judit Presas Escobet
• Matthias Reichert
• Carlota Riba
• Dominique Roulot
• Ana Belén Rubio
• Maria Sánchez-Morata
• Jörn Schattenberg
• Miquel Serra-Burriel
• Feliu Serra-Burriel
• Louise Skovborg Just
• Milan Sonneveld
• Anna Soria
• Christiane Stern
• Patricia Such
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• Pere Toran
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• Paulien van Wijngaarden
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• Ana Viu
• Susanne Nicole Weber
• Tracey Wildsmith

Journal

The Lancet

Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease.

Published Date

2023-07-31

Mayer C, Nehring S, Kucken M, et al

• C. Mayer
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Journal

EMBO Rep

Endoscopic Advances in Hepatology.

Published Date

2023-07-17

Vanderschueren E, Trebicka J, Laleman W

• E. Vanderschueren
• J. Trebicka
• W. Laleman

Journal

Semin Liver Dis

To TIPS or Not to TIPS in High Risk of Variceal Rebleeding and Acute-on-Chronic Liver Failure.

Published Date

2023-07-17

Gu W, Kimmann M, Laleman W, Praktiknjo M, Trebicka J

• W. Gu
• M. Kimmann
• W. Laleman
• M. Praktiknjo
• J. Trebicka

Journal

Semin Liver Dis

Basal MET Phosphorylation is an Indicator of Hepatocyte Dysregulation in Liver Disease (preprint)

Published Date

2023-07-04

Burbano de Lara S, Kemmer S, Biermayer I, et al

• Sebastian Burbano De Lara
• Svenja Kemmer
• Ina Biermayer
• Svenja Feiler
• Artyom Vlasov
• Lorenza D'Alessandro
• Barbara Helm
• Yannik Dieter
• Ahmed Ghallab
• Jan Hengstler
• Professor Dr. med. Katrin Hoffmann
• Marcel Schilling
• Jens Timmer
• Ursula Klingmüller

Journal

bioRxiv

Hepatic inflammatory responses in liver fibrosis.

Published Date

2023-07-03

Hammerich L, Tacke F

• L. Hammerich
• F. Tacke

Journal

Nat Rev Gastroenterol Hepatol

SBOannotator: a Python tool for the automated assignment of systems biology ontology terms

Published Date

2023-07-01

Leonidou N, Fritze E, Renz A, Dräger A

• Nantia Leonidou
• Elisabeth Fritze
• Alina Renz
• Andreas Dräger

Journal

Bioinformatics

Sublethal necroptosis signaling promotes inflammation and liver cancer

Published Date

2023-07-01

Vucur M, Ghallab A, Schneider AT, et al

• Mihael Vucur
• Ahmed Ghallab
• Anne T. Schneider
• Arlind Adili
• Mingbo Cheng
• Mirco Castoldi
• Michael T. Singer
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• Lena Küsgens
• Marlene Kohlhepp
• Boris Görg
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• Jose Efren Barragan Avila
• Kristian Unger
• Claus Kordes
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• Sven H. Loosen
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• Markus S. Jördens
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Journal

Immunity

Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation

Published Date

2023-07-01

Hammad S, Ogris C, Othman A, et al

• Seddik Hammad
• Christoph Ogris
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• Wolfgang Schmidt-Heck
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• Carolina de la Torre
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• Heike Bantel
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• Jan G. Hengstler
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Journal

Cell Death & Disease

Gene regulatory network inference in the era of single-cell multi-omics.

Published Date

2023-06-26

Badia-I-Mompel P, Wessels L, Muller-Dott S, et al

• P. Badia-I-Mompel
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• J. Saez-Rodriguez

Journal

Nat Rev Genet

Acute-On-Chronic Liver Failure: Current Interventional Treatment Options and Future Challenges.

Published Date

2023-06-26

Kimmann M, Trebicka J

• M. Kimmann
• J. Trebicka

Journal

J Pers Med

Efruxifermin, an investigational treatment for fibrotic or cirrhotic nonalcoholic steatohepatitis (NASH)

Published Date

2023-06-03

Puengel T, Tacke F

• Tobias Puengel
• Frank Tacke

Journal

Expert Opinion on Investigational Drugs

Synthesis and In Vitro Biological Evaluation of p-Carborane-Based Di-tert-butylphenol Analogs

Published Date

2023-06-01

Braun S, Jelača S, Laube M, et al

• Sebastian Braun
• Sanja Jelača
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• Sven George
• Bettina Hofmann
• Peter Lönnecke
• Dieter Steinhilber
• Jens Pietzsch
• Sanja Mijatović
• Danijela Maksimović-Ivanić
• Evamarie Hey-Hawkins

Journal

Molecules

Isonimesulide and Its Carborane Analogues as Isoform‐Selective COX Inhibitors and Antitumor Agents

Published Date

2023-05-24

Useini L, Komazec T, Laube M, et al

• Liridona Useini
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• Jonas Schädlich
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• Jens Pietzsch
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Journal

Advanced Therapeutics

Carborane‐Based Tebufelone Analogs and Their Biological Evaluation In Vitro

Published Date

2023-05-24

Braun S, Paskaš S, Laube M, et al

• Sebastian Braun
• Svetlana Paskaš
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• Dieter Steinhilber
• Jens Pietzsch
• Sanja Mijatović
• Danijela Maksimović‐Ivanić
• Evamarie Hey‐Hawkins

Journal

ChemMedChem

Cholangiokines: undervalued modulators in the hepatic microenvironment

Published Date

2023-05-16

Cai X, Tacke F, Guillot A, Liu H

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2023-05-01

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Genes & Diseases

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2023-04-24

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The rationale and study design of two phase II trials examining the effects of BI 685,509, a soluble guanylyl cyclase activator, on clinically significant portal hypertension in patients with compensated cirrhosis.

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2023-04-24

Reiberger T, Berzigotti A, Trebicka J, et al

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2023-04-03

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Journal of Hepatology

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2023-03-27

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2023-03-23

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PLOS Computational Biology

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2023-03-10

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2023-02-21

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2023-02-01

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Molecules

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2023-02-01

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Clinical and Translational Medicine

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2023-01-20

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2023-01-05

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2023-01-01

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Hepatology Communications

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2023-01-01

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Cellular and Molecular Gastroenterology and Hepatology

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2023-01-01

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Cancers

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2023-01-01

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Hepatology

The Multifaceted Roles of Macrophages in NAFLD Pathogenesis

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2023-01-01

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39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber

Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression

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2023-01-01

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Hepatology

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy

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2023-01-01

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Hepatology Communications

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2023-01-01

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39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber

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2022-09-30

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Bioinformatics

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International Journal of Molecular Sciences

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Cell Rep

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2022-08-01

John K, Franck M, Aoua SA, et al

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Journal of Clinical Medicine

Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B

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2022-07-09

Yang G, Zhuang L, Sun T, et al

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Canadian Journal of Gastroenterology and Hepatology

Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

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Deciphering signal transduction networks in the liver by mechanistic mathematical modelling

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2022-06-30

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Biochemical Journal

Fibrogenic Pathways in Metabolic Dysfunction Associated Fatty Liver Disease (MAFLD).

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Int J Mol Sci

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Cells

Hepatic Hedgehog Signaling Participates in the Crosstalk between Liver and Adipose Tissue in Mice by Regulating FGF21

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Ott F, Körner C, Werner K, et al

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Cells

FOXA2 prevents hyperbilirubinaemia in acute liver failure by maintaining apical MRP2 expression

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2022-04-20

Wang S, Feng R, Wang SS, et al

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Gut

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2022-03-07

Feng R, Kan K, Sticht C, et al

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Hepatology

Transforming growth factor β latency: A mechanism of cytokine storage and signalling regulation in liver homeostasis and disease

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2022-02-01

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JHEP Reports

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2022-01-18

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Zeitschrift für Gastroenterologie

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2022-01-18

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Zeitschrift für Gastroenterologie

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2022-01-01

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Bioinformatics Advances

The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis

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2022-01-01

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Hepatology Communications

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2022-01-01

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38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber

Insulin-controlled C/EBPα expression determines the impact of TGF-β on HNF4α transcription in hepatocytes

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2022-01-01

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38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber

Multi-omics profiling identifies molecular signatures of acute-on-chronic liver failure in Abcb4KO mice upon chemical intoxication

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2022-01-01

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38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber

Cold shock protein YB-1 upregulates MDR1 transcription and thus contributes to cholangiocarcinoma chemoresistance to cisplatin

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2022-01-01

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38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber

FOXA2 inhibits hyperbilirubinemia through maintaining apical MRP2 expression in acute liver failure

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2022-01-01

Wang S, Feng R, Wang S, et al

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38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber