Publications
MASLD in the oldest-old: lack of association with cognition or functional autonomy and poor predictive utility of the hepatic steatosis index
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GeroScience
Human assembloids recapitulate periportal liver tissue in vitro
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Nature
Stage-dependent effects of systemic ASBT inhibition in a cholestasis-induced cholemic nephropathy mouse model
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JHEP Reports
NADPH oxidase 1/4 dual inhibition impairs transforming growth factor-beta protumorigenic effects in cholangiocarcinoma cancer-associated fibroblasts
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Signal Transduction and Targeted Therapy
Immunoglobulin G binding as a quantitative marker of hepatocellular death across acute and chronic liver injury
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preprint
OmniPath: integrated knowledgebase for multi-omics analysis
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Nucleic Acids Research
Human Hepatocytes in Experimental Steatosis: Influence of Donor Sex and Sex Hormones
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Biomedicines
Diclofenac and acetaminophen dim the acute-phase response but amplify expression of the iron regulator hepcidin in liver cancer cells
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Cell Systems
In Vitro Characterization of the Published Glypican-3-Targeting Peptide TJ12P2 Reveals a Lack of Specificity and Potency
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Pharmaceuticals
Novel Ruthenacarborane–NSAID Conjugates
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Molecules
Towards sustainable lipidomics: computational screening and experimental validation of chloroform-free alternatives for lipid extraction
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Analytical and Bioanalytical Chemistry
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set
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Nature Communications
Transforming Growth Factor-β Signaling in Alcohol-Associated Liver Disease
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The American Journal of Pathology
AB024. MIST: a weakly supervised deep learning system for multicenter diagnosis of mediastinal tumors
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Mediastinum
Evaluating a population-based screening programme for early detection of liver fibrosis and cirrhosis in primary care in Germany: a cost assessment study
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BMJ Open
SputOMICs identifies common and distinct markers in cystic fibrosis and chronic obstructive pulmonary disease
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preprint
The interplay between biomechanics and cell kinetics explains the spatial pattern in liver fibrosis
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preprint
Investigation and Distinction of Energy Metabolism in Proliferating Hepatocytes and Hepatocellular Carcinoma Cells
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Cells
Deep neural cellular Potts models
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Mouse precision-cut liver and kidney slices: an optimized <i>ex vivo</i> model for acute toxicity testing
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preprint
Overcoming regulatory barriers to the implementation of AI agents in healthcare.
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Nat Med
The barriers for uptake of artificial intelligence in hepatology and how to overcome them
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Journal of Hepatology
ECM1 expression in chronic liver disease: Regulation by EGF/STAT1 and IFNgamma/NRF2 signalling.
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JHEP Rep
LC-MS and High-Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry.
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Angew Chem Int Ed Engl
Exploring the Role of Peripheral Macrophages in Glioma Progression: The Metabolic Significance of Cyclooxygenase-2 (COX-2)
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International Journal of Molecular Sciences
Integrin beta 1 facilitates non-enveloped hepatitis E virus cell entry through the recycling endosome
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Nature Communications
Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
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preprint
TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
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preprint
Patient-specific effects of metformin on the hepatic metabolism in adolescents with metabolic dysfunction-associated steatotic liver disease (MASLD)
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Journal of Molecular Medicine
Comprehensive evaluation of phosphoproteomic-based kinase activity inference
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Nature Communications
The ferroptosis mediator ACSL4 fails to prevent disease progression in mouse models of MASLD
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Hepatology Communications
Non-Alcoholic Beer Influences Glucose and Lipid Metabolism and Changes Body Composition in Healthy, Young, Male Adults
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Nutrients
Carborane‐Based Analogs of Celecoxib and Flurbiprofen, their COX Inhibition Potential, and COX Selectivity Index
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ChemMedChem
Cell Homeostasis or Cell Death—The Balancing Act Between Autophagy and Apoptosis Caused by Steatosis-Induced Endoplasmic Reticulum (ER) Stress
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Cells
Mechanisms underpinning the effect of exercise on the non-alcoholic fatty liver disease: review.
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EXCLI J
ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-beta1 activation.
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Gut
NetworkCommons: bridging data, knowledge, and methods to build and evaluate context-specific biological networks
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Bioinformatics
Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation
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Nature Metabolism