Dr. rer. nat. Laura Feiner
Postdoc - Department of General Surgery at Saarland University Medical Center
Role in LiSyM-Cancer
- Scientific researcher
- Laboratory Head: PD Dr. Claudia Rubie
- Department Chair: Prof. Dr. Matthias Glanemann
- Sample acquisition and biobanking (cryopreserved liver tissue, formalin-fixed paraffin-embedded (FFPE) tissue blocks, blood plasma, and serum)
- Isolation and distribution of primary hepatocytes and primary fibroblasts derived from native liver tissue
- Coordination of sample provision and shipment to consortium partners
Expertise
- The role of epigenetic mechanisms, particularly DNA methylation, in aging and cancer
- Cell culture, ELISA, Western blotting, real-time PCR (qPCR), next-generation sequencing (NGS), DNA methylation analysis
Professional Experience
- Reseach project/networks:
- LiSyM-Cancer Phase I + II – C-TIP-HCC: Mechanism-based Multiscale Model to Dissect the Tipping Point from Liver Cirrhosis to Hepatocellular Carcinoma
- DFG-funded project: Investigation of obesity in relation to the IGF/mTOR signaling pathway, associated regulatory microRNAs, and age-related disease-associated epigenetic alteration.
- HOMFOR-funded project: Investigation of alterations in DNA methylation and gene expression in Werner syndrome as a model of accelerated aging.
Degrees
- PhD (Dr. rer. nat)
2025
Saarland University
PhD thesis at the Department of General Surgery, Visceral, Vascular and Pediatric Surgery, Saarland University Medical Center, Homburg, Germany
Genome-wide investigation of age-associated DNA methylation differences to identify age-associated differentially expressed genes - Master: Medical Biology
2018
University Duisburg-Essen - Bachelor: Applied Life Sciences
2016
Kaiserslautern University of Applied Sciences