Univ.-Prof. Dr. med. Thorsten Cramer

Role in LiSyM-Cancer
– Partner in C-TIP-HCC
– Contributes patient cohorts, samples and data
– Functional experiments with primary cells,
– Establishment of organoids from human liver (normal, cirrhosis and HCC) for functional and intervention assays

Expertise
– Senior physician and experimentalist with specialization in internal medicine/gastroenterology
– Molecular and cellular pathogenesis of solid gastroinestinal and hepatobiliary tumors
– Systemic effects of tumours, e.g. sarcopenia and cachexia, significance of nutrition, the tumour microenvironment (e.g. oxygen deprivation (hypoxia)), chronic inflammatory processes and tumour-specific metabolism for malignant progression
– Effects of dietary changes (e.g. carbohydrate restriction or fasting) on the initiation, progression and treatment of cancer

Degrees
– 1989 – 2006, M.D., Medicine at Freie Universität Berlin

Professional Experience
– Since 2014, Professor of Molecular Tumor Biology at RWTH Aachen University
– 2017 – 2021, Assistant Professor at Maastricht University
– Since 2010, Scientific Editor: Journal of Cachexia, Sarcopenia and Muscle
– 2010 – 2014, Coordinator for Translational Research within the Interdisciplinary Organ Tumor Group “Hepatobiliary Tumors” at the Charité Comprehensive Cancer Center
– 2008 – 2014, Board Member of the Molecular Cancer Research Center at Charité – University Medicine Berlin
– 2003 – 2014, Research Clinician at Charité
– 2001 – 2003, Postdoc, Division of Biology, University of California San Diego

Honors and Awards (selection)

• 2011, Walter-Krienitz-Gedenkpreis of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS)